inflammatory pain — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN2239	Strictosamide		ATPase , Potassium Channel , Sodium Channel , Parasite , Antifungal
	Strictosamide possesses antibacterial and antiviral activities, it also may have important effects on inflammation and inflammatory pain.
T3S2312	Poncirin	Isosakuranetin-7-neohesperidoside	Apoptosis , Others
	1. Poncirin (Isosakuranetin-7-neohesperidoside) shows a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, SGC-791, in a dose-dependent manner. 2. Poncirin prevents adipogenesis, enha...		Apoptosis , Others
T5460	Mofezolac		COX
	Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000		COX
TN6794	N-(3-methoxybenzyl)-octadecanamide		Others
	N-(3-methoxybenzyl)-octadecanamide deverts from Maca (Lepidium meyenii Walp.).		Others
T4542	Clonixin	Clonixic acid	Others
	Clonixin (Clonixic acid) is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. This compound has been reported to block prostaglandin synthesis, and to block inward calcium currents.		Others
T9833	Opiranserin hydrochloride		P2X Receptor , GlyT , 5-HT Receptor
	Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. It shows antagonistic activity on rP2X3 (IC50...		P2X Receptor , GlyT , 5-HT Receptor
TQ0002	A-317491	ABT 202	P2X Receptor
	A-317491 (ABT 202) is a non-nucleotide P2X3 ( Ki: 22 nM) and P2X2/3 receptor (Ki: 9 nM) antagonist, which inhibits calcium flux mediated by the receptors.		P2X Receptor
T2067	NS11394	NS 11394	GABA Receptor
	NS11394 is a effective and subtype-selective GABA(A) receptor-positive modulator; possesses a functional efficacy selectivity profile of α(5) > α(3) > α(2) > α(1) at GABA(A) alpha subunit-containing receptors.		GABA Receptor
T11147	EC5026	BPN-19186	Epoxide Hydrolase
	EC5026 (BPN-19186) has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.		Epoxide Hydrolase
T6950	PNU-120596	NSC 216666	AChR
	PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.		AChR
T1780	Parecoxib	SC 69124,Vorth-P,Valus-P	COX
	Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.		COX
T8579	Nav1.8-IN-1	5-(4-Chlorophenyl)-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]pyridine-3-carboxamide,CHEMBL1270208	Sodium Channel
	Nav1.8-IN-1 (CHEMBL1270208) is an inhibitor of human NaV1.8		Sodium Channel
T7705	GW 405833	L-768242	Cannabinoid Receptor
	GW 405833 (L-768242) is an agonist of cannabinoid-2 (CB(2)) receptor-selective		Cannabinoid Receptor
T16399	Opiranserin		P2X Receptor , GlyT , 5-HT Receptor
	Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is a dual antagonist of glycine transporter type 2 (GlyT2) an...		P2X Receptor , GlyT , 5-HT Receptor
T4561	Tiaprofenic acid	Tiaprofensaeure,Acido tiaprofenico,Surgam	Others , COX
	Tiaprofenic acid (Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.		Others , COX
T16514	PF 04531083		Others , Sodium Channel
	PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.		Others , Sodium Channel
T7722	Feprazone	Prenazone,DA 2370,DA2370,DA-2370	Others
	Feprazone (DA-2370) possesses anti-inflammatory and antiadipogenic properties. Feprazone can be used in studies about the treatment of joint and muscular pain.		Others
T27209	Droxicam	Droxicamum	Others
	Droxicam (Droxicamum) is a non-steroidal anti-inflammatory compound and can be used for research on the relief of inflammation and pain in musculoskeletal disorders.		Others
T14127	Adenosine A1 receptor activator T62		Adenosine Receptor
	Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve...		Adenosine Receptor
T16014	Mavatrep	JNJ-39439335	TRP/TRPV Channel
	Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain.		TRP/TRPV Channel